FORMER U.S. SURGICAL OFFICER JOINS PROTEIN POLYMER TECHNOLOGIES AS SENIOR ADVISOR.

Will Focus on Development of Surgical Sealant Applications Using PPTI’sİ Bioactive Platform Technology

SAN DIEGO, CA – June 26, 2003 -- Protein Polymer Technologies, Inc. (OTC Bulletin Board: PPTI), a company focused on high performance bioactive devices designed for improved surgical outcomes, announced today the hiring of Donald Kaplan, Ph.D., to coordinate the development of the company’s surgical adhesives and sealants program.

Dr. Kaplan is the former Senior Vice President, Operations and Technology at U.S. Surgical Corporation where he was responsible for research and development, quality control, regulatory affairs and manufacturing. U.S. Surgical, now a subsidiary of Tyco, Inc., is an international market leader in the development and sale of surgery and wound closure devices. Prior to U.S. Surgical, Dr. Kaplan was Head of Research and Development at ORMCO, a division of American Hospital Supply. Dr. Kaplan has an extensiveİ background in medical devices, biotechnology, polymer chemistry, and materials science.

The Company recently announced a transitional financing to fund its new strategic plan which includes (1) acceleration of currently active clinical trials and (2) development and partnering of additional bioactive device applications based on the company’s platform technology. In line with the strategic plan, Dr. Kaplan was retained as a senior advisor to focus on the development of surgical sealant and adhesive applications and to coordinate these activities with the overall strategic plan implementation. In addition to his technical leadership, Dr. Kaplan will also help identify potential commercialization and partnership opportunities for the surgical adhesive and sealants technology platform.İ

ìDr. Kaplanís extensive technical background and thorough understanding of the factors that shape demand in the surgical markets add important dimensions to PPTIís product development interests in the surgical sealants and adhesives area. There are a number of potential products which address large markets that can be pursued with our technology, and Dr. Kaplan brings both the expertise and the experience to help us identify and execute our product development and strategic partnering plans in this valuable sector,î commented J. Thomas Parmeter, President and Chief Executive Officer of Protein Polymer Technologies.

Protein Polymer Technologies, Inc., is a San Diego-based company focused on developing products to improve medical and surgical outcomes.İ From its inception in 1988, PPTI has been a pioneer in protein design and synthesis, creating an extensive portfolio of proprietary biomaterials for use in the development of bioactive devices.İ These genetically engineered biomaterials are high molecular weight proteins, processed into products with physical and biological characteristics tailored to specific clinical performance requirements.İ Targeted products include urethral bulking agents for the treatment of stress urinary incontinence, dermal augmentation products for cosmetic and reconstructive surgery, surgical adhesives and sealants, scaffolds for wound healing and tissue engineering, and depots for local drug delivery.İ To date, PPTI has been issued twenty-four U.S. Patents on its core technology with corresponding issued and pending patents in key international markets.

This press release may contain forward-looking statements that are based on management's expectations. Actual results could differ materially from those expressed here; further, the Company is not obligated to comment specifically on those differences. Risks associated with the Company's activities include raising adequate capital to continue operations, scientific and product development uncertainties, competitive products and approaches, continuing collaborative partnership interest and funding, regulatory testing and approvals, and manufacturing scale-up. The reader is encouraged to refer to the Company's Annual Report Form 10-KSB, and recent filings with the Securities and Exchange Commission, copies of which are available from the Company, to further ascertain the risks associated with the above statements.

CONTACTS:

J. Thomas Parmeter
President

John E. Flowersİİİİİİİİİİİ
Vice President, Planning and Operations

(858) 558-6064     e-mail: info@ppti.com