Protein Polymer Technologies Reports First Quarter 1999 Financial Results

    SAN DIEGO, May 17 -- Protein Polymer Technologies, Inc. (Nasdaq: PPTI), reports today its financial results for the first quarter ended March 31, 1999. For the quarter, the Company had a net loss applicable to common shareholders of $1,175,000 ($.11 a share), versus a net loss of $1,347,000 ($.13 a share) for the comparable period a year ago. The net loss and loss per share amounts include accumulated and distributed dividends related to the Company's preferred stock.
    Contract revenues, product and interest income totaled $36,000 for the first quarter ended March 31, 1999, compared to $87,000 for the same period last year. The decrease was due to reduced contract revenues and interest income. Operating expenses for the quarter were $1,142,000, as compared to $1,365,000 for the same period in 1998. The decrease was due primarily to reduced research and development expenses following the completion of preclinical testing and the filing of the Company's Investigational Device Exemption with the U.S. Food and Drug Administration (FDA) requesting permission to initiate human clinical trials of its injectable urethral bulking agent for the treatment of female stress urinary incontinence.
    PPTI's cash balance as of March 31, 1999 was $305,000. Subsequently on April 15, 1999, the Company received approximately $506,000 from the exercise of redeemable warrants issued as part of its initial public offering. On May 12, 1999, the Company received $416,000 from the exercise of warrants issued in conjunction with the sale of its Series E Convertible Preferred Stock. On a pro forma basis as of March 31, 1999, the cash balance including the net amount raised with existing cash would be $1,227,000. At planned spending levels this amount is expected to meet the Company's anticipated capital requirements until July 1999.
    The Company plans to raise additional funds for continuing operations through private or public offerings and collaborative agreements. In addition, the Company is continuing to pursue other strategic alternatives. However, there can be no assurance that any of these fundings will be consummated in the necessary time frames needed for continuing operations or on terms favorable to the Company. If adequate funds are not available, the Company will be required to significantly curtail its operating plans and may have to sell or license out significant portions of the Company's technology or potential products.
   "Our financial results for the quarter reflect a reduction in outside expenditures due to the completion of preclinical testing; additional development expenditures will be required for clinical testing and product registration with the FDA," said J. Thomas Parmeter, PPTI's President and Chief Executive Officer. "While our ability to proceed is entirely dependent on identifying additional sources of working capital, there is continued interest in our programs by potential partners, and we are currently pursuing a number of opportunities. We are in discussions with potential strategic partners for each of the soft tissue augmentation products, and in our redefined surgical adhesives and sealants program, we are seeking to create a partnering relationship with a leading orthopedic device company for the development of a new injectable Spinal disc repair product for the treatment of lower back pain, although there is no assurance that these efforts will ultimately lead to a strategic alliance."
   Protein Polymer Technologies, Inc., is a San Diego-based company focused on developing products to improve medical and surgical outcomes. From its inception in 1988, PPTI has been a pioneer in protein design and synthesis, developing an extensive portfolio of proprietary biomaterials. These genetically engineered biomaterials are high molecular weight proteins, processed into products with physical and biological characteristics tailored to specific clinical performance requirements. Targeted products include urethral bulking agents for the treatment of stress urinary incontinence, dermal augmentation products for cosmetic and reconstructive surgery, surgical adhesives and sealants, adhesive fillers for repair of Spinal discs, scaffolds for wound healing and tissue engineering, and depots for local drug delivery.
  

This press release may contain forward-looking statements that are based on management's expectations. Actual results could differ materially from those expressed here; further, the Company is not obligated to comment specifically on those differences. Risks associated with the Company's activities include raising adequate capital to continue operations, scientific and product development uncertainties, competitive products and approaches, continuing collaborative partnership interest and funding, regulatory testing and approvals, and manufacturing scale-up. The reader is encouraged to refer to the Company's Annual Report Form 10-KSB, and recent filings with the Securities and Exchange Commission, copies of which are available from the Company, to further ascertain the risks associated with the above statements.


                      PROTEIN POLYMER TECHNOLOGIES, INC.

                        Condensed Financial Statements

                                 (unaudited)



                                                 Three months ended 

                                                       March 31,     

    SUMMARY OF OPERATIONS                     1999                1998       



    Contract revenue                      $     --            $ 53,750   

    Product and other income                22,649              25,039 

    Interest income                         13,002               8,656

    Total revenues                          35,651              87,445



    Total expenses                       1,141,751           1,364,682



    Net loss                            (1,106,100)         (1,277,237)



    Undeclared and/or paid     

      dividends on Preferred Stock          69,410              71,113



    Net loss applicable to 

     common shareholders               $(1,174,559)        $(1,346,804)



    Net loss per common share -

     basic and diluted                       (0.11)              (0.13)



    Shares used in computing net

     loss per share -

     basic and diluted                  10,940,748          10,429,094





                                          As of              As of

                                      Mar. 31, 1999      Dec. 31, 1998

    BALANCE SHEET INFORMATION                               (audited)



    Cash, cash equivalents and

    short-term investments              $  305,113          $1,380,000

    Working capital                       (437,307)            600,000

    Total assets                         1,095,205           2,225,231

    Total capital invested              34,284,395          34,258,000

    Accumulated deficit                (34,094,064)        (32,988,000)